A circulating reservoir of pathogenic-like CD4(+) T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

OBJECTIVES: Systemic immunological processes are profoundly shaped by the micro-environments where antigen recognition occurs. Identifying molecular signatures distinctive of such processes is pivotal to understand pathogenic immune responses and manipulate them for therapeutic purposes. Unfortunate...

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Bibliografiske detaljer
Udgivet i:	Ann Rheum Dis
Main Authors:	Spreafico, Roberto, Rossetti, Maura, van Loosdregt, Jorg, Wallace, Carol A, Massa, Margherita, Magni-Manzoni, Silvia, Gattorno, Marco, Martini, Alberto, Lovell, Daniel J, Albani, Salvatore
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMJ Publishing Group 2016
Fag:	Basic and Translational Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4752664/ https://ncbi.nlm.nih.gov/pubmed/25498120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-206226
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A circulating reservoir of pathogenic-like CD4(+) T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

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