Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells

OBJECTIVES: JIA is an autoimmune disease involving disturbed T-cell homeostasis, marked by highly activated effector T cells. Autophagy, a lysosomal degradation pathway, is crucial for maintaining cellular homeostasis by regulating the survival, differentiation and function of a large variety of cel...

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Bibliografiske detaljer
Udgivet i:Rheumatology (Oxford)
Main Authors: Peeters, Janneke G. C., de Graeff, Nienke, Lotz, Martin, Albani, Salvatore, de Roock, Sytze, van Loosdregt, Jorg
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Clinical Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850277/
https://ncbi.nlm.nih.gov/pubmed/28957547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kex227
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