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Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells
OBJECTIVES: JIA is an autoimmune disease involving disturbed T-cell homeostasis, marked by highly activated effector T cells. Autophagy, a lysosomal degradation pathway, is crucial for maintaining cellular homeostasis by regulating the survival, differentiation and function of a large variety of cel...
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Publicado no: | Rheumatology (Oxford) |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5850277/ https://ncbi.nlm.nih.gov/pubmed/28957547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kex227 |
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