Renal Cell Carcinomas in Vinylidene Chloride Exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation

Vinylidene Chloride (VDC) has been widely used in the production of plastics and flame retardants. Exposure of B6C3F1 mice to VDC in the 2-year National Toxicology Program carcinogenicity bioassay resulted in a dose-dependent increases in renal cell hyperplasia, adenoma, and carcinoma (RCCs). Among...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Toxicol Pathol
Asıl Yazarlar: Hayes, Schantel A., Pandiri, Arun R., Ton, Thai-vu T., Hong, Hue-Hua L., Clayton, Natasha P., Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin, Wyde, Michael, Sills, Robert C., Hoenerhoff, Mark J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752433/
https://ncbi.nlm.nih.gov/pubmed/26682919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623315610820
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller