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Direct Activation of Bax Protein for Cancer Therapy
Bax, a central cell death regulator, is an indispensable gateway to mitochondrial dysfunction and a major pro-apoptotic member of the Bcl-2 family proteins that control apoptosis in normal and cancer cells. Dysfunction of apoptosis renders the cancer cell resistant to treatment as well as promotes t...
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| Veröffentlicht in: | Med Res Rev |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4752390/ https://ncbi.nlm.nih.gov/pubmed/26395559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.21379 |
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