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Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma

Anti-angiogenic therapy is a promising therapeutic strategy for the highly vascular and malignant brain tumor, glioblastoma (GBM), although current clinical trials have failed to demonstrate an extension in overall survival. The small molecule tyrosine kinase inhibitor axitinib that targets vascular...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Neurooncol
Päätekijät: Lu, Lei, Saha, Dipongkor, Martuza, Robert L., Rabkin, Samuel D., Wakimoto, Hiroaki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751887/
https://ncbi.nlm.nih.gov/pubmed/25213669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1612-1
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