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Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma

Anti-angiogenic therapy is a promising therapeutic strategy for the highly vascular and malignant brain tumor, glioblastoma (GBM), although current clinical trials have failed to demonstrate an extension in overall survival. The small molecule tyrosine kinase inhibitor axitinib that targets vascular...

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Bibliografski detalji
Izdano u:J Neurooncol
Glavni autori: Lu, Lei, Saha, Dipongkor, Martuza, Robert L., Rabkin, Samuel D., Wakimoto, Hiroaki
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751887/
https://ncbi.nlm.nih.gov/pubmed/25213669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1612-1
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