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Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma

Anti-angiogenic therapy is a promising therapeutic strategy for the highly vascular and malignant brain tumor, glioblastoma (GBM), although current clinical trials have failed to demonstrate an extension in overall survival. The small molecule tyrosine kinase inhibitor axitinib that targets vascular...

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Bibliografiske detaljer
Udgivet i:J Neurooncol
Main Authors: Lu, Lei, Saha, Dipongkor, Martuza, Robert L., Rabkin, Samuel D., Wakimoto, Hiroaki
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751887/
https://ncbi.nlm.nih.gov/pubmed/25213669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1612-1
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