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Combinatorial effects of VEGFR kinase inhibitor axitinib and oncolytic virotherapy in mouse and human glioblastoma stem-like cell models

PURPOSE: Glioblastoma (GBM), a fatal brain cancer, contains a subpopulation of GBM stem-like cells (GSCs) that contribute to resistance to current therapy. Angiogenesis also plays a key role in GBM progression. Therefore, we developed a strategy to target the complex GBM microenvironment, including...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Saha, Dipongkor, Wakimoto, Hiroaki, Peters, Cole, Antoszczyk, Slawomir J., Rabkin, Samuel D., Martuza, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050085/
https://ncbi.nlm.nih.gov/pubmed/29599413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1717
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