Regional heritability mapping method helps explain missing heritability of blood lipid traits in isolated populations

Single single-nucleotide polymorphism (SNP) genome-wide association studies (SSGWAS) may fail to identify loci with modest effects on a trait. The recently developed regional heritability mapping (RHM) method can potentially identify such loci. In this study, RHM was compared with the SSGWAS for blo...

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Vydáno v:Heredity (Edinb)
Hlavní autoři: Shirali, M, Pong-Wong, R, Navarro, P, Knott, S, Hayward, C, Vitart, V, Rudan, I, Campbell, H, Hastie, N D, Wright, A F, Haley, C S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751621/
https://ncbi.nlm.nih.gov/pubmed/26696135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2015.107
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