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An Evolutionary Perspective on Epistasis and the Missing Heritability

The relative importance between additive and non-additive genetic variance has been widely argued in quantitative genetics. By approaching this question from an evolutionary perspective we show that, while additive variance can be maintained under selection at a low level for some patterns of epista...

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Detalhes bibliográficos
Main Authors: Hemani, Gibran, Knott, Sara, Haley, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585114/
https://ncbi.nlm.nih.gov/pubmed/23509438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003295
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