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Evolutionary perspectives on polygenic selection, missing heritability, and GWAS
Genome-wide association studies (GWAS) have successfully identified many trait-associated variants, but there is still much we do not know about the genetic basis of complex traits. Here, we review recent theoretical and empirical literature regarding selection on complex traits to argue that “missi...
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| Publicado no: | Hum Genet |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8059781/ https://ncbi.nlm.nih.gov/pubmed/31201529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-019-02040-6 |
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