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Nerve Growth Factor Is Regulated by Toll-Like Receptor 2 in Human Intervertebral Discs

Nerve growth factor (NGF) contributes to the development of chronic pain associated with degenerative connective tissue pathologies, such as intervertebral disc degeneration and osteoarthritis. However, surprisingly little is known about the regulation of NGF in these conditions. Toll-like receptors...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Krock, Emerson, Currie, J. Brooke, Weber, Michael H., Ouellet, Jean A., Stone, Laura S., Rosenzweig, Derek H., Haglund, Lisbet
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751394/
https://ncbi.nlm.nih.gov/pubmed/26668319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675900
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