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Toll-like receptor 2 induced senescence in intervertebral disc cells of patients with back pain can be attenuated by o-vanillin

BACKGROUND: There is an increased level of senescent cells and toll-like teceptor-1, -2, -4, and -6 (TLR) expression in degenerating intervertebral discs (IVDs) from back pain patients. However, it is currently not known if the increase in expression of TLRs is related to the senescent cells or if i...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Mannarino, Matthew, Cherif, Hosni, Li, Li, Sheng, Kai, Rabau, Oded, Jarzem, Peter, Weber, Michael H., Ouellet, Jean A., Haglund, Lisbet
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051055/
https://ncbi.nlm.nih.gov/pubmed/33863359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-021-02504-z
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