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Toll-like Receptor Activation Induces Degeneration of Human Intervertebral Discs
Toll-like receptors (TLR) are activated by endogenous alarmins such as fragmented extracellular matrix compounds found in the degenerating disc. TLRs regulate cytokine, neurotrophin, and protease expression in human disc cells in vitro, and thus control key factors in disc degeneration. However, whe...
保存先:
| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5719358/ https://ncbi.nlm.nih.gov/pubmed/29215065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17472-1 |
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