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Unscheduled DNA Synthesis: A Functional Assay for Global Genomic Nucleotide Excision Repair

The unscheduled DNA synthesis (UDS) assay measures a cell’s ability to perform global genomic nucleotide excision repair (NER). This chapter provides instructions for the application of this technique by creating 6-4 photoproducts and pyrimidine dimers using UVC irradiation. Repair is quantified by...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Methods Mol Biol
Main Authors: Kelly, Crystal M., Latimer, Jean J.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751077/
https://ncbi.nlm.nih.gov/pubmed/15502232
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