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Amplification of unscheduled DNA synthesis signal enables fluorescence-based single cell quantification of transcription-coupled nucleotide excision repair

Nucleotide excision repair (NER) comprises two damage recognition pathways: global genome NER (GG-NER) and transcription-coupled NER (TC-NER), which remove a wide variety of helix-distorting lesions including UV-induced damage. During NER, a short stretch of single-stranded DNA containing damage is...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Wienholz, Franziska, Vermeulen, Wim, Marteijn, Jurgen A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436002/
https://ncbi.nlm.nih.gov/pubmed/28088761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1360
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