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Mammalian Transcription-Coupled Excision Repair

Transcriptional arrest caused by DNA damage is detrimental for cells and organisms as it impinges on gene expression and thereby on cell growth and survival. To alleviate transcriptional arrest, cells trigger a transcription-dependent genome surveillance pathway, termed transcription-coupled nucleot...

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Bibliographic Details
Main Authors: Vermeulen, Wim, Fousteri, Maria
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721277/
https://ncbi.nlm.nih.gov/pubmed/23906714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012625
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