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A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair

Transcription-coupled nucleotide excision repair (TC-NER) allows RNA polymerase II (RNAPII)-blocking lesions to be rapidly removed from the transcribed strand of active genes. Defective TCR in humans is associated with Cockayne syndrome (CS), typically caused by defects in either CSA or CSB. Here, w...

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Detalhes bibliográficos
Main Authors: Anindya, Roy, Mari, Pierre-Olivier, Kristensen, Ulrik, Kool, Hanneke, Giglia-Mari, Giuseppina, Mullenders, Leon H., Fousteri, Maria, Vermeulen, Wim, Egly, Jean-Marc, Svejstrup, Jesper Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885502/
https://ncbi.nlm.nih.gov/pubmed/20541997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.04.017
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