A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair

Transcription-coupled nucleotide excision repair (TC-NER) allows RNA polymerase II (RNAPII)-blocking lesions to be rapidly removed from the transcribed strand of active genes. Defective TCR in humans is associated with Cockayne syndrome (CS), typically caused by defects in either CSA or CSB. Here, w...

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Hoofdauteurs: Anindya, Roy, Mari, Pierre-Olivier, Kristensen, Ulrik, Kool, Hanneke, Giglia-Mari, Giuseppina, Mullenders, Leon H., Fousteri, Maria, Vermeulen, Wim, Egly, Jean-Marc, Svejstrup, Jesper Q.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885502/
https://ncbi.nlm.nih.gov/pubmed/20541997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.04.017
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