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Unscheduled DNA Synthesis: The Clinical and Functional Assay for Global Genomic DNA Nucleotide Excision Repair

The unscheduled DNA synthesis (UDS) assay measures the ability of a cell to perform global genomic nucleotide excision repair (NER). This chapter provides instructions for the application of this technique by creating 6-4 photoproducts and pyrimidine dimers using UV-C irradiation. This procedure is...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Latimer, Jean J., Kelly, Crystal M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751080/
https://ncbi.nlm.nih.gov/pubmed/24623250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-739-6_36
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