Systemic Chromosome Instability (CIN) resulted in colonic transcriptomic changes in metabolic, proliferation, and stem cell regulators in Sgo1-/+ mice

Colon cancer is the second most lethal cancer and is predicted to claim 49,700 lives in the U.S this year. Chromosome Instability (CIN) is observed in 80–90% of colon cancers and is thought to contribute to colon cancer progression and recurrence. To investigate the impact of CIN on colon cancer dev...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Rao, Chinthalapally V., Sanghera, Saira, Zhang, Yuting, Biddick, Laura, Reddy, Arun, Lightfoot, Stan, Janakiram, Naveena B., Mohammed, Altaf, Dai, Wei, Yamada, Hiroshi Y.
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750399/
https://ncbi.nlm.nih.gov/pubmed/26833665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0940
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