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Antagonizing Pathways Leading to Differential Dynamics in Colon Carcinogenesis in Shugoshin1 (Sgo1)-Haploinsufficient Chromosome Instability Model

Colon cancer is the second most lethal cancer. It is predicted to claim 50,310 lives in 2014. Chromosome Instability (CIN) is observed in 80-90% of colon cancers, and is thought to contribute to colon cancer progression and recurrence. However, there are no animal models of CIN that have been valida...

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Détails bibliographiques
Publié dans:Mol Carcinog
Auteurs principaux: Rao, Chinthalapally V., Sanghera, Saira, Zhang, Yuting, Biddick, Laura, Reddy, Arun, Lightfoot, Stan, Dai, Wei, Yamada, Hiroshi Y.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569547/
https://ncbi.nlm.nih.gov/pubmed/25773652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22306
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