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Spontaneous development of Alzheimer's disease‐associated brain pathology in a Shugoshin‐1 mouse cohesinopathy model

Spontaneous late‐onset Alzheimer's disease (LOAD) accounts for more than 95% of all human AD. As mice do not normally develop AD and as understanding on molecular processes leading to spontaneous LOAD has been insufficient to successfully model LOAD in mouse, no mouse model for LOAD has been av...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Rao, Chinthalapally V., Farooqui, Mudassir, Zhang, Yuting, Asch, Adam S., Yamada, Hiroshi Y.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052391/
https://ncbi.nlm.nih.gov/pubmed/29943428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12797
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