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Spontaneous development of Alzheimer's disease‐associated brain pathology in a Shugoshin‐1 mouse cohesinopathy model

Spontaneous late‐onset Alzheimer's disease (LOAD) accounts for more than 95% of all human AD. As mice do not normally develop AD and as understanding on molecular processes leading to spontaneous LOAD has been insufficient to successfully model LOAD in mouse, no mouse model for LOAD has been av...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Aging Cell
Main Authors: Rao, Chinthalapally V., Farooqui, Mudassir, Zhang, Yuting, Asch, Adam S., Yamada, Hiroshi Y.
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052391/
https://ncbi.nlm.nih.gov/pubmed/29943428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12797
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