GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells

Advances in the scalable production of blood cells from induced pluripotent stem cells (iPSCs) open prospects for the clinical translation of de novo generated blood products, and evoke the need for preclinical evaluation of their efficacy, safety, and immunogenicity in large animal models. Due to s...

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Publicat a:Stem Cell Reports
Autors principals: D'Souza, Saritha S., Maufort, John, Kumar, Akhilesh, Zhang, Jiuchun, Smuga-Otto, Kimberley, Thomson, James A., Slukvin, Igor I.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750098/
https://ncbi.nlm.nih.gov/pubmed/26805448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.12.010
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