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NOTCH activation at the hematovascular mesoderm stage facilitates efficient generation of T cells with high proliferation potential from human pluripotent stem cells

Human pluripotent stem cells (hPSCs) offer the potential to serve as a versatile and scalable source of T cells for immunotherapies, which could be coupled with genetic engineering technologies to meet specific clinical needs. In order to improve T cell production from hPSCs it is essential to ident...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kumar, Akhilesh, Lee, Jeong Hee, Suknantha, Kran, D’Souza, Saritha S., Thakur, Abir S., Slukvin, Igor I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344284/
https://ncbi.nlm.nih.gov/pubmed/30578305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801027
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