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GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells

Advances in the scalable production of blood cells from induced pluripotent stem cells (iPSCs) open prospects for the clinical translation of de novo generated blood products, and evoke the need for preclinical evaluation of their efficacy, safety, and immunogenicity in large animal models. Due to s...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: D'Souza, Saritha S., Maufort, John, Kumar, Akhilesh, Zhang, Jiuchun, Smuga-Otto, Kimberley, Thomson, James A., Slukvin, Igor I.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750098/
https://ncbi.nlm.nih.gov/pubmed/26805448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.12.010
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