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Metabolic disruption identified in the Huntington’s disease transgenic sheep model
Huntington’s disease (HD) is a dominantly inherited, progressive neurodegenerative disorder caused by a CAG repeat expansion within exon 1 of HTT, encoding huntingtin. There are no therapies that can delay the progression of this devastating disease. One feature of HD that may play a critical role i...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749952/ https://ncbi.nlm.nih.gov/pubmed/26864449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20681 |
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