Targeting matriptase in breast cancer abrogates tumor progression via impairment of stromal-epithelial growth factor signaling

Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years due to its consistent dysregulation in human epithelial tumors, including breast cancer. Mice with reduced levels of matriptase display a significant delay in oncogene-induc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Zoratti, Gina L., Tanabe, Lauren M., Varela, Fausto A., Murray, Andrew S., Bergum, Christopher, Colombo, Eloic, Lang, Julie, Molinolo, Alfredo A., Leduc, Richard, Marsault, Eric, Boerner, Julie, List, Karin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749267/
https://ncbi.nlm.nih.gov/pubmed/25873032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7776
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge