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Targeting matriptase in breast cancer abrogates tumor progression via impairment of stromal-epithelial growth factor signaling
Matriptase is an epithelia-specific membrane-anchored serine protease that has received considerable attention in recent years due to its consistent dysregulation in human epithelial tumors, including breast cancer. Mice with reduced levels of matriptase display a significant delay in oncogene-induc...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4749267/ https://ncbi.nlm.nih.gov/pubmed/25873032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7776 |
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