Matriptase Proteolytically Activates Influenza Virus and Promotes Multicycle Replication in the Human Airway Epithelium

Influenza viruses do not encode any proteases and must rely on host proteases for the proteolytic activation of their surface hemagglutinin proteins in order to fuse with the infected host cells. Recent progress in the understanding of human proteases responsible for influenza virus hemagglutinin ac...

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Autors principals: Beaulieu, Alexandre, Gravel, Émilie, Cloutier, Alexandre, Marois, Isabelle, Colombo, Éloïc, Désilets, Antoine, Verreault, Catherine, Leduc, Richard, Marsault, Éric, Richter, Martin V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624356/
https://ncbi.nlm.nih.gov/pubmed/23365447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03005-12
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