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Design and Synthesis of Potent, Selective Inhibitors of Matriptase

[Image: see text] Matriptase is a member of the type II transmembrane serine protease family. Several studies have reported deregulated matriptase expression in several types of epithelial cancers, suggesting that matriptase constitutes a potential target for cancer therapy. We report herein a new s...

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Detalhes bibliográficos
Main Authors: Colombo, Éloïc, Désilets, Antoine, Duchêne, Dominic, Chagnon, Félix, Najmanovich, Rafael, Leduc, Richard, Marsault, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4025795/
https://ncbi.nlm.nih.gov/pubmed/24900505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml3000534
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