Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds

G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-strand breaks (DSBs) arising at collapsed forks. We have previously...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Zimmer, Jutta, Tacconi, Eliana M.C., Folio, Cecilia, Badie, Sophie, Porru, Manuela, Klare, Kerstin, Tumiati, Manuela, Markkanen, Enni, Halder, Swagata, Ryan, Anderson, Jackson, Stephen P., Ramadan, Kristijan, Kuznetsov, Sergey G., Biroccio, Annamaria, Sale, Julian E., Tarsounas, Madalena
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747901/
https://ncbi.nlm.nih.gov/pubmed/26748828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.12.004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados