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Unstable FoxP3(+) T regulatory cells in NZW mice

Regulatory T (Treg) cells that express the transcription factor FoxP3 play a key role in self-tolerance and the control of inflammation. In mice and humans, there is a wide interindividual range in Treg frequency, but little is known about the underlying genetic or epigenetic mechanisms. We explored...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Dépis, Fabien, Kwon, Ho-Keun, Mathis, Diane, Benoist, Christophe
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747713/
https://ncbi.nlm.nih.gov/pubmed/26768846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524660113
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