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Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3

FoxP3(+) T regulatory (Treg) cells have a fundamental role in immunological tolerance, with transcriptional and functional phenotypes that demarcate them from conventional CD4(+) T cells (Tconv). Differences between these two lineages in the signaling downstream of T-cell receptor-triggered activati...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Yan, Dapeng, Farache, Julia, Mingueneau, Michael, Mathis, Diane, Benoist, Christophe
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4672803/
https://ncbi.nlm.nih.gov/pubmed/26627244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520393112
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