Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization

The cysteine cathepsins are a group of 11 proteases whose function was originally believed to be the degradation of endocytosed material with a high degree of redundancy. However, it has become clear that these enzymes are also important regulators of both health and disease. Thus, selective tools t...

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Detaylı Bibliyografya
Yayımlandı:J Am Chem Soc
Asıl Yazarlar: Bender, Kristina Oresic, Ofori, Leslie, van der Linden, Wouter A., Mock, Elliot D., Data, Gopal, Chowdhury, Somenath, Li, Hao, Segal, Ehud, Lopez, Mateo Sanchez, Ellman, Jonathan A., Figdor, Carl G., Bogyo, Matthew, Verdoes, Martijn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747655/
https://ncbi.nlm.nih.gov/pubmed/25785540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b00315
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