Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the US. Cancer-associated cachexia is present in up to 80% of PDAC patients and is associated with aggressive disease and poor prognosis. In the present studies we evaluated an anti-cancer natural product...

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Vydáno v:Oncotarget
Hlavní autoři: Shukla, Surendra K., Dasgupta, Aneesha, Mehla, Kamiya, Gunda, Venugopal, Vernucci, Enza, Souchek, Joshua, Goode, Gennifer, King, Ryan, Mishra, Anusha, Rai, Ibha, Nagarajan, Sangeetha, Chaika, Nina V., Yu, Fang, Singh, Pankaj K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747396/
https://ncbi.nlm.nih.gov/pubmed/26510913
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