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Macrophages Potentiate STAT3 Signaling in Skeletal Muscles and Regulate Pancreatic Cancer Cachexia
Incidence of cachexia is highly prevalent in pancreatic ductal adenocarcinoma (PDAC); advanced disease stage directly correlates with decreased muscle and fat mass in PDAC patients. The pancreatic tumor microenvironment is central to the release of systemic factors that govern lipolysis, proteolysis...
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| Udgivet i: | Cancer Lett |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7286478/ https://ncbi.nlm.nih.gov/pubmed/32344015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.04.017 |
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