Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related deaths in the US. Cancer-associated cachexia is present in up to 80% of PDAC patients and is associated with aggressive disease and poor prognosis. In the present studies we evaluated an anti-cancer natural product...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shukla, Surendra K., Dasgupta, Aneesha, Mehla, Kamiya, Gunda, Venugopal, Vernucci, Enza, Souchek, Joshua, Goode, Gennifer, King, Ryan, Mishra, Anusha, Rai, Ibha, Nagarajan, Sangeetha, Chaika, Nina V., Yu, Fang, Singh, Pankaj K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747396/
https://ncbi.nlm.nih.gov/pubmed/26510913
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