Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia

BACKGROUND: Aberrant energy metabolism is a hallmark of cancer. To fulfill the increased energy requirements, tumor cells secrete cytokines/factors inducing muscle and fat degradation in cancer patients, a condition known as cancer cachexia. It accounts for nearly 20% of all cancer-related deaths. H...

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Main Authors: Shukla, Surendra K, Gebregiworgis, Teklab, Purohit, Vinee, Chaika, Nina V, Gunda, Venugopal, Radhakrishnan, Prakash, Mehla, Kamiya, Pipinos, Iraklis I, Powers, Robert, Yu, Fang, Singh, Pankaj K
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2014
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4165433/
https://ncbi.nlm.nih.gov/pubmed/25228990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-2-18
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