Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells

[Image: see text] Pancreatic cancer cells overexpressing Mucin 1 (MUC1) rely on aerobic glycolysis and, correspondingly, are dependent on glucose for survival. Our NMR metabolomics comparative analysis of control (S2–013.Neo) and MUC1-overexpressing (S2–013.MUC1) cells demonstrates that MUC1 reprogr...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Gebregiworgis, Teklab, Purohit, Vinee, Shukla, Surendra K., Tadros, Saber, Chaika, Nina V., Abrego, Jaime, Mulder, Scott E., Gunda, Venugopal, Singh, Pankaj K., Powers, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5634392/
https://ncbi.nlm.nih.gov/pubmed/28809118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00246
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