A randomized phase 3 study on the optimization of the combination of bevacizumab with FOLFOX/OXXEL in the treatment of patients with metastatic colorectal cancer-OBELICS (Optimization of BEvacizumab scheduLIng within Chemotherapy Scheme)

BACKGROUND: Despite the improvements in diagnosis and treatment, colorectal cancer (CRC) is the second cause of cancer deaths in both sexes. Therefore, research in this field remains of great interest. The approval of bevacizumab, a humanized anti-vascular endothelial growth factor (VEGF) monoclonal...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Avallone, Antonio, Piccirillo, Maria Carmela, Aloj, Luigi, Nasti, Guglielmo, Delrio, Paolo, Izzo, Francesco, Di Gennaro, Elena, Tatangelo, Fabiana, Granata, Vincenza, Cavalcanti, Ernesta, Maiolino, Piera, Bianco, Francesco, Aprea, Pasquale, De Bellis, Mario, Pecori, Biagio, Rosati, Gerardo, Carlomagno, Chiara, Bertolini, Alessandro, Gallo, Ciro, Romano, Carmela, Leone, Alessandra, Caracò, Corradina, de Lutio di Castelguidone, Elisabetta, Daniele, Gennaro, Catalano, Orlando, Botti, Gerardo, Petrillo, Antonella, Romano, Giovanni M., Iaffaioli, Vincenzo R., Lastoria, Secondo, Perrone, Francesco, Budillon, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746902/
https://ncbi.nlm.nih.gov/pubmed/26857924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2102-y
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