Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: results of the branch trial

BACKGROUND: We have previously shown that an intensified preoperative regimen including oxaliplatin plus raltitrexed and 5-fluorouracil/folinic acid (OXATOM/FUFA) during preoperative pelvic radiotherapy produced promising results in locally advanced rectal cancer (LARC). Preclinical evidence suggest...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Avallone, Antonio, Pecori, Biagio, Bianco, Franco, Aloj, Luigi, Tatangelo, Fabiana, Romano, Carmela, Granata, Vincenza, Marone, Pietro, Leone, Alessandra, Botti, Gerardo, Petrillo, Antonella, Caracò, Corradina, Iaffaioli, Vincenzo R., Muto, Paolo, Romano, Giovanni, Comella, Pasquale, Budillon, Alfredo, Delrio, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745808/
https://ncbi.nlm.nih.gov/pubmed/26320185
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