Effect of Bevacizumab in Combination With Standard Oxaliplatin-Based Regimens in Patients With Metastatic Colorectal Cancer: A Randomized Clinical Trial

IMPORTANCE: Although bevacizumab is a standard of care in combination treatments for metastatic colorectal cancer (mCRC), its clinical benefit has been limited. OBJECTIVE: To determine whether sequential scheduling of bevacizumab administration in combination with chemotherapy improves treatment eff...

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Pubblicato in:JAMA Netw Open
Autori principali: Avallone, Antonio, Piccirillo, Maria C., Nasti, Guglielmo, Rosati, Gerardo, Carlomagno, Chiara, Di Gennaro, Elena, Romano, Carmela, Tatangelo, Fabiana, Granata, Vincenza, Cassata, Antonino, Silvestro, Lucrezia, De Stefano, Alfonso, Aloj, Luigi, Vicario, Valeria, Nappi, Anna, Leone, Alessandra, Bilancia, Domenico, Arenare, Laura, Petrillo, Antonella, Lastoria, Secondo, Gallo, Ciro, Botti, Gerardo, Delrio, Paolo, Izzo, Francesco, Perrone, Franco, Budillon, Alfredo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2021
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8314140/
https://ncbi.nlm.nih.gov/pubmed/34309665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2021.18475
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