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Targeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancers

Despite significant advances in early detection and treatment, breast cancer still remains a major cause of morbidity and mortality for women. Our understanding of the molecular heterogeneity of the disease has significantly expanded over the past decade and the role of cell cycle signaling in both...

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Détails bibliographiques
Publié dans:Breast Cancer Res
Auteurs principaux: Finn, Richard S., Aleshin, Alexey, Slamon, Dennis J.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746893/
https://ncbi.nlm.nih.gov/pubmed/26857361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0661-5
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