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Redifferentiation of expanded human islet β cells by inhibition of ARX
Ex-vivo expansion of adult human islet β cells has been evaluated for generation of abundant insulin-producing cells for transplantation; however, lineage-tracing has demonstrated that this process results in β-cell dedifferentiation. Redifferentiation of β-cell-derived (BCD) cells can be achieved u...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746595/ https://ncbi.nlm.nih.gov/pubmed/26856418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20698 |
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