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Inhibition of ZEB1 expression induces redifferentiation of adult human β cells expanded in vitro
In-vitro expansion of functional adult human β-cells is an attractive approach for generating insulin-producing cells for transplantation. However, human islet cell expansion in culture results in loss of β-cell phenotype and epithelial-mesenchymal transition (EMT). This process activates expression...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532995/ https://ncbi.nlm.nih.gov/pubmed/26264186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13024 |
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