Insulin-Producing Cells Generated from Dedifferentiated Human Pancreatic Beta Cells Expanded In Vitro

BACKGROUND: Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, attempts at expanding human islet cells in tissue culture result in loss of beta-cell phenotype. Using a lineage-t...

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Hlavní autoři: Russ, Holger A., Sintov, Elad, Anker-Kitai, Leeat, Friedman, Orr, Lenz, Ayelet, Toren, Ginat, Farhy, Chen, Pasmanik-Chor, Metsada, Oron-Karni, Varda, Ravassard, Philippe, Efrat, Shimon
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184150/
https://ncbi.nlm.nih.gov/pubmed/21984932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025566
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