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Insulin-Producing Cells Generated from Dedifferentiated Human Pancreatic Beta Cells Expanded In Vitro

BACKGROUND: Expansion of beta cells from the limited number of adult human islet donors is an attractive prospect for increasing cell availability for cell therapy of diabetes. However, attempts at expanding human islet cells in tissue culture result in loss of beta-cell phenotype. Using a lineage-t...

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Detalhes bibliográficos
Main Authors: Russ, Holger A., Sintov, Elad, Anker-Kitai, Leeat, Friedman, Orr, Lenz, Ayelet, Toren, Ginat, Farhy, Chen, Pasmanik-Chor, Metsada, Oron-Karni, Varda, Ravassard, Philippe, Efrat, Shimon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184150/
https://ncbi.nlm.nih.gov/pubmed/21984932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025566
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