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Redifferentiation of Adult Human β Cells Expanded In Vitro by Inhibition of the WNT Pathway
In vitro expansion of adult human islet β cells is an attractive solution for the shortage of tissue for cell replacement therapy of type 1 diabetes. Using a lineage tracing approach we have demonstrated that β-cell-derived (BCD) cells rapidly dedifferentiate in culture and can proliferate for up to...
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| Publicado no: | PLoS One |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231080/ https://ncbi.nlm.nih.gov/pubmed/25393025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112914 |
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