In silico Analysis of HIV-1 Env-gp120 Reveals Structural Bases for Viral Adaptation in Growth-Restrictive Cells

Variable V1/V2 and V3 loops on human immunodeficiency virus type 1 (HIV-1) envelope-gp120 core play key roles in modulating viral competence to recognize two infection receptors, CD4 and chemokine-receptors. However, molecular bases for the modulation largely remain unclear. To address these issues,...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Yokoyama, Masaru, Nomaguchi, Masako, Doi, Naoya, Kanda, Tadahito, Adachi, Akio, Sato, Hironori
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746247/
https://ncbi.nlm.nih.gov/pubmed/26903989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00110
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