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Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip

Molecular interactions of the variable envelope gp120 subunit of HIV-1 with two cellular receptors are the first step of viral infection, thereby playing pivotal roles in determining viral infectivity and cell tropism. However, the underlying regulatory mechanisms for interactions under gp120 sponta...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Koma, Takaaki, Yokoyama, Masaru, Kotani, Osamu, Doi, Naoya, Nakanishi, Nina, Okubo, Hayato, Adachi, Shun, Adachi, Akio, Sato, Hironori, Nomaguchi, Masako
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315996/
https://ncbi.nlm.nih.gov/pubmed/33883222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02177-20
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